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BES 511 - Nutrition and Epigenetics

Graduate Education Institute · Nutrition and Dietetics · Master

ECTS: 7.5 T+P+L: 3+0+0 Departmental Elective
Coordinator: Doç. Dr. Serap ANDAÇ

Course Objective

Epigenetics is to learn the etiology-related bases of human nutrition, environmental factors and nutrition-related diseases, to identify the possible mechanisms of these relationships, and to interpret the results of these relationships in animal studies and epidemiological studies.

Course Content

In this course, basic genetic concepts, DNA methylation, histone modification and so on. mechanisms that alter gene expression through nutrition, and the role of these processes in the formation and / or prevention of nutrition-related diseases.

Required Resources

Current research and review articles

Course Learning Outcomes

  1. Beslenme ile ilişkili epigenetik mekanizmalar hakkında bilgi edinilir
  2. Beslenme ile ilişkili hastalıkların önlenmesinde epigenetik ve optimal beslenmenin önemi hakkında bilgi ve beceriler geliştirilir
  3. Epigenetiğin toplum sağlığı ve beslenmesi açısından önemi değerlendirilir
  4. Epigenetik mekanizmalarda fonksiyonu olan spesifik besin öğelerinin etkisi ve önemi konusunda bilgi edinilir
  5. Epigenetik mekanizmaların beslenme ile ilişkili hastalıklar üzerindeki etkisi değerlendirilir

Core Area Distribution

(42) Life Sciences%20 (72) Health%80

Teaching Methods

ExpressionQuestion-AnswerDiscussionGroup StudySelf studyProject Based Learning (Including Field Work)

Assessment & Evaluation

HomeworkPerformance Assignment ( Lab / Workshop / Field Work / Seminar / Presentation / Completion Study / ThesisTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)

ECTS / Workload

ActivityQuantityDuration (h)Total Workload
Course Duration (Including Exam Week)16348
Out of Class Study Period16696
Midterm11010
Quiz000
Assignment12525
Practice000
Final11010

Course Schedule

WeekSubjectPreparation
1Introduction to geneticsLesson materials will be shared
2Basis principles in epigenetics: DNA methylation and histone modificationsLesson materials will be shared
3Basis principles in epigenetics: chromatin remodelling, RNA and other microDNAsLesson materials will be shared
4Epigenetic mechanisms in diseases- CancerLesson materials will be shared
5Epigenetic mechanisms in diseases, Type 2 diabetesLesson materials will be shared
6Epigenetic mechanisms in diseases, obesity, metabolic syndromeLesson materials will be shared
7Epigenetics and specific nutrients: Folate and B12Lesson materials will be shared
8MidtermMidterm
9Epigenetics and specific nutrients: Protein and energyLesson materials will be shared
10Epigenetics and environmental factors: Diethanolamine, bisphenol ALesson materials will be shared
11Epigenetics and environmental factors: Arsenic, nickel, chromiumLesson materials will be shared
12Epigenetics and epidemiologyLesson materials will be shared
13Student presentations (Epigenetic mechanisms, disease and nutrition)Lesson materials will be shared
14Student presentations (Epigenetic mechanisms, disease and nutrition)Lesson materials will be shared
15Student presentations (Epigenetic mechanisms, disease and nutrition)Lesson materials will be shared
16Final ExaminationFinal Examination