HEM 509 - Pathophysiology

Graduate Education Institute · Internal Medicine Nursing · Master

ECTS: 7.5 T+P+L: 3+0+0 Departmental Elective
Coordinator: Doç. Dr. Aklime SARIKAYA

Course Objective

The aim of this course is to gain knowledge and skills about the physiological and pathological processes in homeostasis, cells, organs and systems, the main causes of the changes that may occur in systems in case of illness, their mechanisms, the signs, findings and basic treatment approaches.

Course Content

This course includes the physiopathological changes in cell, organ and system levels; cell and tissue physiology, gene and genetic diseases, fluid electrolyte, acid base imbalance, cell injury, inflammation, immunity, infection, immunodeficiency, stress and diseases, oncogenesis, neurological, endocrine, hematological, cardiovascular, pulmonary, renal, digestive, muscle Mechanisms of disease and skin system diseases, diagnosis and treatment principles.

Required Resources

5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.

 

Recommended Resources

6. Kumar V, Abbas A, Fousta N, Mitchell R. Robbins (2017) Basic Pathology, 10th International Edition.  Saunders Book Company. ISBN:9780323480543

Explanations

Evaluation of the course:

Achievement: 30% Midterm + 20% Homework + 50% Final exam = 100%

The mid-term and final exams of the course will consist of open-ended questions.

In the course work, each student will prepare and share a topic and a relevant case statement. The paper will deliver the report as a 13-week report in the case of the word file.

Assignments will be evaluated by using the subject content and case based on scientific and up-to-date information

Rules

Students must attend 70% of the course. Each student has to follow the course to continue. The student who cannot fulfill the condition of attendance can not take the Final and make-up exam.

The course must be entered in time.

Course Learning Outcomes

  1. To be able to explain genetic environmental interaction and genetic diseases
  2. To be able to explain the mechanisms of cell communication, cell injury, cell death
  3. Explain cell cycle and its changes, mechanisms of action of oncogenesis and neoplastic treatments
  4. To be able to explain the effects of liquid-electrolyte / acid-base imbalances at cell and system level,
  5. Explain the defense systems of the body, inflammation, immune response and changes, pathogenesis of infection
  6. To be able to explain and interpret the physiopathology, symptoms, diagnosis and the relationship between treatment methods

Core Area Distribution

(72) Health%100

Teaching Methods

ExpressionQuestion-AnswerDiscussionCase StudySelf study

Assessment & Evaluation

HomeworkTesting (Essay / Tests: True-Falls, multiple-choice, short answer, matching)

ECTS / Workload

ActivityQuantityDuration (h)Total Workload
Course Duration (Including Exam Week)16348
Out of Class Study Period16348
Midterm11515
Quiz000
Assignment11010
Practice000
Final13535

Course Schedule

WeekSubjectPreparation
1Explanation of the curriculum, objectives, evaluation and assignments5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
2Cell structure, function and pathophysiological changes in diseases5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
3Liquid-electrolyte / acid-base imbalances and edema mechanism- case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
4Defense systems: inflammation and infection-case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
5Defense systems:Immune response and hypersensitivity immunodeficiency- case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
6Genetic relationship between environmental and genetic diseases -olg analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
7Oncogenesis- case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
8Midterm exam5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
9Hemodynamic alterations, thrombosis and shock- case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
10Cardiovascular system diseases - case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
11Respiratory system disorders - case analysis Renal system disorders-case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
12Neurological disorders-case analysis Endocrine disorders - case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
13Musculoskeletal system diseases-case analysis Gastrointestinal system diseases-case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
14Pain and Temperature; sepsis -case analysis5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
15Assessment of the course and feedback5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.
16Final exam5. McCance KL, Huether SE. (2008) Pathophysiology The Biologic Basis For  Disease in Adults and Children, The C.V. Mosby Company, StLouis.